Skip to content
Medical Health Aged Care, Seniors Interest

Review highlights menopause research gaps and calls for a new definition

Monash University 2 mins read

A team of international experts has called for a new definition of menopause, more research and improved treatments following a comprehensive review published in the journal Cell.


Led by
Monash University Women’s Health Research Program head Professor Susan Davis, the review summarised menopause knowledge, called for more research into its timeline and treatment, and encouraged individualised, holistic treatment that addressed symptoms and systemic body changes.


“The road to menopause is not difficult for all, but for some, symptoms may be severe or even disabling and disruptive to work and family,” the Australian, Italian and US-based authors wrote.

“Recognition that menopause, for most women, is a natural biological event, does not exempt the use of interventions to alleviate symptoms. Optimising health at menopause is the gateway to healthy ageing for women.”

 

The researchers looked at more than 200 sources across 71 years to synthesise current knowledge. Key takeaways included:

  • A proposed new definition for menopause as “final cessation of ovarian function,” rather than the traditional focus on menstruation. Among other things this would encompass those without regular periods before menopause, who used certain types of contraception like IUDs, and had hysterectomies.
  • The timeline of menopause phases isn’t well understood and varies from person to person, so age restrictions on prescriptions and therapies are problematic and not always logical.
  • Menopause treatments range from hormone therapies to lasers to plant products, but few have been studied over long enough timespans.
  • Each treatment type has potential side effects and health concerns. Even the most effective and well-researched—hormone therapy targeting oestrogen—is far from a perfect solution for all.
  • Symptoms vary widely, from severe to none. Even if someone has no noticeable symptoms, there can still be significant “silent health consequences,” including bone loss and a higher risk of diabetes, cardiovascular diseases, and certain cancers.
  • Some symptoms, like short-term memory loss, can be temporary, and others, like depression and anxiety, can be pre-existing conditions falsely attributed to menopause due to stigma surrounding it.
  • Regular exercise and maintaining a protein-rich nutritious diet can reduce the likelihood of symptomatic health complications.
  • Socio-economic factors such as lower quality of life and the potential negative impact of menopausal symptoms on a woman’s work performance aren't often acknowledged.


Despite decades of menopause research, Prof
essor Davis and her colleagues said researchers needed to look deeper into when the process started and focus on making treatments more effective and safer overall.

 

They also underlined the importance of research outside high-income countries, and studying the impacts of menopause on work from home and in an office, as well as the impacts on people with less traditional career paths such as caregivers and volunteers.


Professor Davis and her co-authors said menopause treatments needed to be holistic and individually tailored, addressing physical and mental health impacts, as well as underlying associated health risks and any other relevant health concerns.

Optimal menopause-related care involves shared decision making which means quality, evidence-based information needs to be available for the general community and health care providers,” Professor Davis said.


Cell, Davis et al. “Menopause – Biology, Consequences, Supportive Care and Therapeutic Options.”
https://www.cell.com/cell/fulltext/S0092-8674(23)00905-4
DOI:
http://dx.doi.org/10.1016/j.cell.2023.08.016


To download a copy of this paper, please visit: https://www.dropbox.com/scl/fo/wckzxvs480w956rai3gea/h?rlkey=h9669gs8bteq7yzt60nset1lf&dl=0


For media enquiries please contact:

 

Author Contact:
Susan R Davis
Monash University
susan.davis@monash.edu


Monash University

Cheryl Critchley - Communications Manager (medical)
E:
cheryl.critchley@monash.edu

T: +61 (0) 418 312 596

 

For more Monash media stories, visit our news and events site 


For general media enquiries please contact:
Monash Media
E: 
media@monash.edu
T: +61 (0) 3 9903 4840

 

***ENDS***

 

More from this category

  • Medical Health Aged Care
  • 27/05/2024
  • 14:21
Dementia Australia

Community turns out in force to support people impacted by dementia

Thank you to Brisbane community members who turned up in force to the 2024 Memory Walk & Jog, showing their support for Australians living with dementia. More than 1,200 people walked, ran and jogged on Sunday 26 May raising an impressive total of $135,000! Dementia Australia Executive Director Services, Advocacy & Research Dr Kaele Stokes said it was a wonderful occasion and extended her gratitude to all who participated, raised funds, spread the word and donated. “There was an outstanding show of support from the Brisbane community who turned out in such large numbers for another year. So many people…

  • Contains:
  • Medical Health Aged Care
  • 27/05/2024
  • 13:09
UNSW Sydney

Ozempic found to reduce risk of kidney disease and death in people with diabetes

A popular diabetes medication has been found to prevent kidney failure and reduce deaths in people with type 2 diabetes and chronic kidney disease. Antidiabetic medication semaglutide, more widely known by brand names Ozempic and Wegovy, significantly reduces the risk of kidney failure, substantial loss of kidney function and death from kidney or cardiovascular causes, an international clinical trial led by UNSW Sydney researchers has shown. The trial involving more than 3500 participants with type 2 diabetes and chronic kidney disease from 28 countries – including Australia, the USA and China – found a small weekly dose of semaglutide reduced…

  • Medical Health Aged Care
  • 27/05/2024
  • 12:24
Dementia Australia

Community turns out in force to support people impacted by dementia

Thank you to Perth community members who turned up in force to the 2024 Memory Walk & Jog, showing their support for Australians living with dementia. More than 1,000 people walked, ran and jogged on Sunday 26 May raising an impressive total of $140,000! Dementia Australia Executive Director Services, Advocacy & Research Dr Kaele Stokes said it was a wonderful occasion and extended her gratitude to all who participated, raised funds, spread the word and donated. “There was an outstanding show of support from the Perth community who turned out in such large numbers for another year. So many people…

  • Contains:

Media Outreach made fast, easy, simple.

Feature your press release on Medianet's News Hub every time you distribute with Medianet. Pay per release or save with a subscription.