- Latest Australian research reveals 28,265 cases of aggressive types of early-onset bowel cancer over the past 30 years
- Incidence increased by up to 8% per year; if this increase had been prevented, an estimated 4,347 bowel cancers in young Australians would not have occurred
- Bowel cancer incidence is 2 to 3-fold higher among Australians born in the 1990s vs 1950s
Tuesday 27 May 2025, Sydney: Latest Australian researchⁱ reveals 28,265 cases of aggressive types of early-onset bowel cancer over the past 30 years, including an estimated 4,347 additional early-onset bowel cancer cases attributable to the rising rates of the disease.
An early release of findings (published in medRxiv) from a study conducted by University of Melbourne researchers examined bowel cancer rates among those aged 20 to 49 (‘early-onset’) and over across a thirty-year period (1990-2020).
It found rising early-onset colon cancer rates resulted in 2,398 excess cases, or a 26% increase in observed cases compared to expected numbers if the increase did not occur. Similarly, rising early-onset rectal cancer rates resulted in 1,949 excess cases or a 20% increase.
Author Professor Mark Jenkins, University of Melbourne said, “Our inability to halt the rising burden of early-onset bowel cancer over the last thirty-years has resulted in over 4,300 excess cases being diagnosed among young Australians.”
“Notably, we found bowel cancer incidence was 2 to 3-fold higher among Australians born in the 1990s versus 1950s, suggesting increasing prevalence or earlier exposure to risk factors. The increase is occurring even for the most aggressive forms of the disease. However, the underlying causes remain unknown,” lead author Aaron Meyers, University of Melbourne added.
The Australian research further supports international research published in The Lancetⁱⁱ, which reveals Australia now has the highest rates of early-onset bowel cancer in the world, with a faster increase found in women than in men.
The international research compared bowel cancer rates in those aged under and over 50 in 50 countries worldwide. It found early-onset bowel cancer increased in 27 of the 50 countries in the last decade until 2017, a rise no longer confined to high-income western countries.
Bowel Cancer Australia CEO, Julien Wiggins, said “The research showed the rising incidence of early-onset bowel cancer had continued at 2 to 4% annually until 2017. However, bowel cancer rates among those over 50 were falling in many of the countries studied, including Australia.”
“In 2024, it is estimated to be the deadliest cancer from men and the second deadliest cancer for women under 50,” he added.
“This risk of being diagnosed before age 40 has more than doubled since 2000, and 1-in-9 new bowel cancer cases now occur in people under age 50.”
“As screening is not routinely offered to people at average risk under 45, we need to improve awareness among GPs and the public about the red flag signs and symptoms of early-onset bowel cancer,” Mr Wiggins said.
“This remains the primary opportunity for early detection provided young people received prompt colonoscopy referral to rule out bowel cancer as an underlying cause of their symptoms.”
ENDS
June is Bowel Cancer Awareness Month – Bowel Cancer Australia’s signature event to raise awareness of Australia’s second deadliest cancer and funds for the leading community-funded charity dedicated to championing what matters most to people impacted by bowel cancer and empowering everyone affected to live their best life.
Bowel Cancer Australia’s latest awareness campaign, Australia’s Deadliest, features four early-onset patients, Nina, Jake, Rachel and Kin to highlight the impact of this disease on younger Australians. The 60 second film can be viewed here: https://www.youtube.com/watch?v=_PdAKd1mKKI
Bowel Cancer Australia’s Never2Young Advocacy Agenda seeks to improve care experiences and health outcomes for younger people by championing:
• Greater awareness: among the community and health professionals of early-onset bowel cancer.
• Lower screening age: in response to the increasing rates of bowel cancer in younger people.
• Prompt GP referral: to a colonoscopy for all younger people who present with symptoms that may be consistent with bowel cancer.
• Improved pathways: that ensure timely triage, diagnosis, and treatment for younger people.
• Better understanding: the challenges of early-onset bowel cancer to improve and tailor treatment, support, and care for younger patients.
• Further research: into the causes of early-onset bowel cancer, that has the potential to improve survival and/or help build a path toward a cure.
i Meyers AL, Dowty JG, Mahmood K, Macrae FA, Rosty C, Buchanan DD, Jenkins MA. Age-specific trends in colorectal, appendiceal, and anal tumour incidence by histological subtype in Australia from 1990 to 2020: a population-based time-series analysis. medRxiv [Preprint]. 2025 Apr 24:2025.04.21.25326138. doi: 10.1101/2025.04.21.25326138. PMID: 40313308; PMCID: PMC12045447.
ii Sung, Hyuna et al. Colorectal cancer incidence trends in younger versus older adults: an analysis of population-based cancer registry data. The Lancet Oncology, Volume 26, Issue 1, 51 - 63
Contact details:
For an interview with a medical expert or patient contact:
Stephanie Bansemer-Brown – Bowel Cancer Australia
[email protected] | 0412 915 797
